Glutamate decarboxylase (GAD)

a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO2 as well as l-aspartate to 3-aminopropanoate and CO2; a defect in the binding of this protein's coenzyme is believed to cause pyridoxine dependency with seizures. SYN: aspartate 1-decarboxylase.

Chemwatch
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