an explanation of the allosteric form of cooperativity. In this model, in the absence of ligands, the oligomeric protein exists in only one conformation; on binding, the ligand induces a conformational change that may be transmitted to other subunits. SYN: Adair-Koshland-Némethy-Filmer model, induced fit model (2). [Daniel E. Koshland, George Némethy, David L. Filmer]
