Diffuse type giant cell tumor

locally invasive tumor of joints and periarticular soft tissues composed of mononuclear fibroblastic cells, and hemosiderin-filled macrophages; mitoses are prominent and larger tumors show invasive growth and tendency to recur. These tumors are similar to localized giant cell tumor of soft tissues but are more cellular, show nuclear atypia, prominent nucleoli, and distinct chromosomal changes. Recurrence occurs in 30-50% cases; in rare cases they may be frankly malignant.

Chemwatch
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.