Olfactory Neuroblastomas are rare neuroectodermal tumors. They are assumed to originate from olfactory receptor cells high in the nasal cavity. Unless resected at an early stage, they carry a poor prognosis. Microscopically, their typical pattern is neuroblastic with occasional formation of rosettes, but some lesions show neuroendocrine differentiation. When this pattern dominates the histology, the diagnosis of a neuro-endocrine carcinoma may occur. (Adapted from WHO.)
