small firm spheroidal or irregular foci that are yellow-brown, brown, or rusted color, occurring chiefly in the spleen in such conditions as congestive splenomegaly and sickle cell disease, and consisting of relatively dense fibrous tissue or collagenous fibers impregnated with iron pigment and calcium salts; probably result from organization and scarring of sites where small perivascular hemorrhages occurred. SYN: Gamna-Gandy nodules, Gandy-Gamna bodies, siderotic nodules.
