Hyperosmolar (hyperglycemic) nonketotic coma

a complication seen in diabetes mellitus (q.v.) in which very marked hyperglycemia occurs (such as levels exceeding 800 mg/dL), causing osmotic shifts in water in brain cells, and resulting in coma. It can be fatal or lead to permanent neurologic damage. Ketoacidosis does not occur in these cases. SYN: nonketotic hyperglycemia.

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