(1) a manifestation of major mood disorder involving enduring periods of persistent and significant elevated, expansive, or irritable mood, and associated symptoms including decreased sleep, psychomotor speeding, racing thoughts, flight of ideas, grandiosity, and poor judgment leading to behavior that may later be regretted. SYN: mania.affective disorders, under disorder, endogenous depression, manic-depressive, manic excitement (2) a DSM construct with specified criteria.bipolar disorder, affective disorders, under disorder, manic-depressive, manic excitement