Bronchopulmonary dysplasia

A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS. Severity of this disease and lung injuries depend on the duration of oxygen supplementation, positive pressure requirement, GESTATIONAL AGE, and BIRTH WEIGHT of the infant.