a zoonosis transmitted between humans and other animals from an infected to a susceptible host by contact, by airborne droplets or droplet nuclei, or by some vehicle of transmission; the agent requires a single vertebrate host for completion of its life cycle and does not develop or show significant change during transmission; may include anthropozoonoses (rabies), zooanthroponoses (amebiasis), and amphixenoses (certain staphylococcoses).