Disseminated intravascular coagulation (DIC)

a hemorrhagic syndrome that occurs following the uncontrolled activation of clotting factors and fibrinolytic enzymes throughout small blood vessels; fibrin is deposited, platelets and clotting factors are consumed, and fibrin degradation products inhibit fibrin polymerization, resulting in tissue necrosis and bleeding.consumption coagulopathy, fibrinogen-fibrin conversion syndrome.