Keratinocyte growth factor 2

Encoded by human FGF10 Gene (FGF Family), secreted 208-aa 23-kDa (precursor) Fibroblast Growth Factor 10 contains 2 putative N-glycosylation sites, a heparin binding domain, and several putative phosphorylation sites and is involved in epidermal brain, lung, and limb bud morphogenesis. Most similar to FGF7, FGF10 is mitogenic in the lung and for keratinizing epidermal cells. FGF10 also appears to be involved tissue repair/wound healing. (NCI)