An autosomal dominant form of limb-girdle muscular dystrophy where muscle weakness and atrophy is caused by mutations of chromosome 7q31.1. The muscle weakness starts in the muscles close to the trunk and spreads to the ends of the limbs. Early onset may result in wheelchair dependence by the 4th decade. The rate of progression is variable. See also Muscular dystrophy, limb-girdle, autosomal dominant, type 1F