a rearrangement of the Michaelis-Menten equation, 1/v = 1/Vmax + (Km/Vmax)(1/[S]), where v is the velocity of the reaction, Vmax is the maximum velocity, Km is the Michaelis constant; and [S] is the substrate concentration. Cf.: double-reciprocal plot [Hans Lineweaver, Dean Burk]