Lissencephaly due to chromosome 17 anomalies (medical condition)

A rare brain malformation where the surface of the brain is smoother than normal. Type 1 is caused by a defect on the LIS1 gene on chromosome 17p13.3. The severity of the symptoms are variable depending on the severity of the brain abnormality. Miller-Dieker syndrome is a subtype of this condition. See also Lissencephaly type 1, due to LIS 1 anomalies

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