[MIM*309350] a generalized skeletal dysplasia with prominent forehead and small mandible; radiographically, there are irregular ribbonlike constrictions of the ribs and tubular bones; probably X-linked [MIM*309350]. Autosomal dominant and recessive inheritance [MIM*249420] have also been suggested. SYN: Melnick-Needles syndrome, osteodysplasty.