Peripheral sensory neuropathy, autosomal dominant (PSN) (medical condition)

CMT is an inherited neurological disease characterized by the gradual degeneration of nerves which starts in the hands and feet and results in progressive numbness, muscle weakness and loss of function. Type 2B has an autosomal dominant inheritance and involves a defect in the gene for the protein RAB 7 located on chromosome 3. See also Charcot-Marie-Tooth disease, Type 2B