PHA1 (medical condition)

A rare condition characterized by electrolyte disorders caused by the kidney's inability to respond to mineralocorticoids. Type 1 is differentiated from type II in that it involves sodium wasting. There are two forms of type 1: an autosomal recessive form which tends to be more severe than the autosomal dominant form. The recessive form tends to persist into adulthood whereas the dominant form is milder and symptoms tend to improve with age. See also Pseudohypoaldosteronism type 1, autosomal recessive