REAL classification

a classification of lymphoma first published in 1994 and based on the correlation of clinical features of lymphomas with their histopathology and immunophenotype and genotype of neoplastic cells; groups lymphoproliferative diseases into chronic leukemia/lymphoma, nodal or extranodal lymphoma, acute leukemia lymphoma, plasma cell disorders, and Hodgkin disease. [Revised European-American lymphoma classification]