(sil-vәs-tre´ne kor´dah) a rare syndrome seen in certain persons with cirrhosis , consisting of eunuchoid body type, loss of body hair, decreased libido, and sterility; affected males have atrophy of the testes and gynecomastia , and affected females have menstrual disorders such as menorrhagia or amenorrhea . It results from abnormally high estrogenic activity due to failure of the liver to inactivate the circulating estrogens .